Conclusion: Unintended consequences of HIT affect collaboration between healthcare workers. The consequences may be both desirable and undesirable. Previous research has mostly focused on the undesirable unintended consequences. We show that the introduction of e-messaging led to both desirable and undesirable unintended consequences for interprofessional collaboration. More insight into positive unintended consequences can be a resource in the reorganisation of work that often accompanies the implementation of HIT. (Source: International Journal of Medical Informatics).