Abstract: Objectives: The integration of Human Factors is still insufficient in the design and implementation phases of complex interactive systems such as Computerized Physician Order Entry (CPOE) systems. One of the problems is that human factors specialists have difficulties to communicate their data and to have them properly understood by the computer scientists in the design and implementation phases. This paper presents a solution to this problem based on the creation of common documentation supports using Software Engineering (SE) and Human–Computer Interaction (HCI) methods.Method: The integration of SE and HCI methods and models is an interesting means for modelling an organization’s activities, with software applications being part of these activities. Integrating these SE and ….