Authors: Elkin PL, Froehling D, Wahner-Roedler D, Trusko B, Welsh G, Rosenbloom ST, Speroff T, Brown SH
In this manuscript we report an evaluation of the reliability of clinical research rules creation by multiple clinicians using the Health Archetype Language (HAL-42) and user interface. HAL-42 is a language which allows real time epidemiological inquiry using automatically derived clinical encodings with any health Ontology. This evaluation used SNOMED CT as the underlying Ontology. The inquiries were performed on a population of 17,731 patients whose 50,000 clinical records have all been fully encoded in SNOMED CT. Four subject matter experts (SMEs) were asked independently to encode and run 10 rules/studies. The inter-rater agreement was 74.8{ca7ad0b74511a57bb2016f24c729dd7716d5352e92d2275aa1f91fb22c36b0a7} (p=0.6526) with a Kappa statistic of 0….