Funding Opportunity RFA-AA-12-009 from the NIH Guide for Grants and Contracts. This FOA issued by the National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, solicits cooperative agreement grant applications (U01) to develop and strategically test coordinated interventions to reduce alcohol use and alcohol-related consequences in HIV-impacted populations. In addition, this research seeks to develop a new framework for sustainable implementation research among HIV+ alcohol users, with the ultimate goal of significantly improving health care systems. This initiative intends to build on existing cohorts of HIV+ patients, including those who have been diagnosed recently and are just entering treatment, and those who are well-established in HIV treatment.